US $300, UK £175 * – single user license – online fulfillment
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Full Feature List
Enzyme Kinetics and Curve Fitting
EnzFitter is a generic curve-fitting package which has custom
features designed to make it especially suitable for analysis
of enzyme kinetics experiments. For example, initial rate and
parameter values can be obtained with their confidence limits
for single and twin substrate rate data. Built-in models include
Michaelis-Menten with or without substrate inhibition, competitive,
uncompetitive and mixed inhibition, ternary complex or ordered bi-bi
systems and ping-pong with and without inhibition by substrates. You
can easily add other models in conventional algebraic syntax.
Data import formats include EnzFitter for DOS files as well as ASCII
delimited, dBase, FoxPro, Excel, Quattro Pro, Lotus 123, Paradox and
Symphony. File and dataset sizes are limited only by available memory
and multiple data sets can be created for each file. There are advanced
data editing facilities including: insert/edit/remove points, copy and
move blocks of data and edit column titles. Missing data and replicates
are catered for. Descriptive statistics of the data can be displayed and
exported. The worksheet is customizable (e.g. font, colors, borders, row
height and column width) and when data are printed they can be given custom
headers or footers. You can insert new columns or rows at any time. Many
data transforms are supplied or you can create your own equations for
transforms. You can create templates for data formats you use frequently
which, combined with graph templates virtually automate routine assays.
Multiple curve fits can be performed for any data set using either the
Marquardt or Simplex algorithms. Optionally, data can be weighted robustly,
statistically, proportionally or with explicit values. A genetic algorithm
generates excellent initial parameter estimates but parameters can be
constrained to a range of values or fixed when necessary. The results are
presented in tabular and graphic form and can be saved to disk, printed or
exported to other programs. Export formats include, for graphs, Bitmaps,
Metafiles, JPG or TIF and, for numeric results, ASCII delimited and Excel.
Graphs of raw and fitted data can be plotted and, to distinguish datasets,
you can select a variety of symbols, semi-continuous lines and also add
labels. Subsidiary graphs of extra sets of data, residuals and transformed
/derivative plots of the same data can be inset on the main graph.
EnzFitter can be set up to run in batch mode (performing several analyses
automatically, without user intervention) and it also supports OLE Automation.
For more general assay use, you can calculate unknowns from fitted standard
curves. You can create text Notes that are attached to any file, dataset or
curve fit. There is also an automatic Logbook which records all changes made
to a given file.
* Single user license US $300/ UK £175
5 user license US $900/ UK £525
10 user license US $1500/UK £875
The above prices are for online fulfillment only and include user manual as .pdf
An additional charge of $90/£50 is made for supply of hard copy (CD) if required